Concurrent Chemotherapy and Radiotherapy for Organ Preservation in Advanced Laryngeal Cancer

20033,151 citationsJournal Articlebronze Open Access

Authors

Arlene A. Forastiere · Sidney Kimmel Comprehensive Cancer Center

Helmuth Goepfert · The University of Texas MD Anderson Cancer Center

Moshe Maor · The University of Texas MD Anderson Cancer Center

Thomas F. Pajak · RTOG Foundation

Randal S. Weber · The University of Texas MD Anderson Cancer Center

William H. Morrison · The University of Texas MD Anderson Cancer Center

Bonnie S. Glisson

Abstract

In patients with laryngeal cancer, radiotherapy with concurrent administration of cisplatin is superior to induction chemotherapy followed by radiotherapy or radiotherapy alone for laryngeal preservation and locoregional control.

Topics & Keywords

Head and Neck Cancer Studies Voice and Speech Disorders Tracheal and airway disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 349, Issue 22, pp. 2091-2098

DOI: 10.1056/nejmoa031317

Field-Weighted Citation Impact: 87.65