Microvascular network alterations in the retina of patients with Alzheimer's disease

2014315 citationsJournal Article

Authors

Carol Y. Cheung · Singapore National Eye Center

Yi Ting Ong · Singapore National Eye Center

M. Kamran Ikram · National University Health System

Shin Yeu Ong · Singapore National Eye Center

Xiang Li · Singapore Eye Research Institute

Saima Hilal · National University Health System

Joseree‐Ann S. Catindig

Abstract

Patients with AD have altered microvascular network in the retina (narrower retinal venules and a sparser and more tortuous retinal vessels) compared with matched nondemented controls. These changes in retinal microvasculature may reflect similar pathophysiological processes in cerebral microvasculature in the brains of patients with AD.

Topics & Keywords

Retinal Imaging and Analysis Glaucoma and retinal disorders Retinal Diseases and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alzheimer s & Dementia

Volume 10, Issue 2, pp. 135-142

DOI: 10.1016/j.jalz.2013.06.009

Field-Weighted Citation Impact: 17.44