Morphine Inhibits Spontaneous and Cytokine-enhanced Natural Killer Cell Cytotoxicity in Volunteers

1995307 citationsJournal Articlebronze Open Access

Authors

Mark P. Yeager · Dartmouth–Hitchcock Medical Center

Thomas A. Colacchio · Dartmouth College

Paul M. Guyre · Dartmouth College

Abstract

These results suggest that morphine administration, at doses within the range of analgesic use, can cause measurable suppression of some components of the human cellular immune system.

Topics & Keywords

Cancer, Stress, Anesthesia, and Immune Response Neuropeptides and Animal Physiology Pharmacological Receptor Mechanisms and Effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 83, Issue 3, pp. 500-508.

DOI: 10.1097/00000542-199509000-00008

Field-Weighted Citation Impact: 7.56