Metaplastic breast carcinomas are basal‐like tumours

2006341 citationsJournal Articlegold Open Access

Authors

J. S. Reis-Filho · Breast Cancer Now

Fernanda Milanezi · University of Minho

D Steele · Breast Cancer Now

Kay Savage · Breast Cancer Now

Peter T. Simpson · Royal Brisbane and Women's Hospital

J M Nesland · Norwegian Cancer Society

Emílio Marcelo Pereira ·

Abstract

Our results demonstrate that MBCs show a basal-like phenotype, regardless of the type of metaplastic elements. Moreover, as these neoplasms frequently overexpress EGFR (57%), patients with MBC may benefit from treatment with anti-EGFR drugs.

Topics & Keywords

Breast Cancer Treatment Studies HER2/EGFR in Cancer Research Cancer and Skin Lesions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Histopathology

Volume 49, Issue 1, pp. 10-21

DOI: 10.1111/j.1365-2559.2006.02467.x

Field-Weighted Citation Impact: 15.01