The immune cell infiltrate populating meningiomas is composed of mature, antigen-experienced T and B cells

201391 citationsJournal Articlebronze Open Access

Authors

Liangjuan Fang · Central South University

Daniel E. Lowther · Yale University

Matthew L. Meizlish · Central South University

Richard C. E. Anderson · Third Xiangya Hospital

Jeffrey N. Bruce · Columbia University

Lesley Devine · St. Joseph's Hospital and Medical Center

Anita Hüttner

Abstract

The tumor microenvironment of meningiomas often includes postgerminal center B cell populations. These tumors invariably include a selected, antigen-experienced, effector T cell population enriched by those that express markers of an exhausted phenotype.

Topics & Keywords

Meningioma and schwannoma management Neurofibromatosis and Schwannoma Cases Myasthenia Gravis and Thymoma

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neuro-Oncology

Volume 15, Issue 11, pp. 1479-1490

DOI: 10.1093/neuonc/not110

Field-Weighted Citation Impact: 3.26