Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

2009644 citationsJournal Article

Authors

Allen J. Taylor · MedStar Washington Hospital Center

Todd C. Villines · Walter Reed Army Institute of Research

Eric J. Stanek

Patrick J. Devine · Walter Reed Army Institute of Research

Len Griffen

Michael Miller · Walter Reed Army Institute of Research

Neil J. Weissman · MedStar Washington Hospital Center

Mark Turco

Abstract

This comparative-effectiveness trial shows that the use of extended-release niacin causes a significant regression of carotid intima-media thickness when combined with a statin and that niacin is superior to ezetimibe. (ClinicalTrials.gov number, NCT00397657.)

Topics & Keywords

Lipoproteins and Cardiovascular Health Cancer, Lipids, and Metabolism Diabetes, Cardiovascular Risks, and Lipoproteins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 361, Issue 22, pp. 2113-2122

DOI: 10.1056/nejmoa0907569

Field-Weighted Citation Impact: 112.67