Use of Salsalate to Target Inflammation in the Treatment of Insulin Resistance and Type 2 Diabetes

2008293 citationsJournal Articlebronze Open Access

Authors

Allison B. Goldfine · Joslin Diabetes Center

Robert Silver · Joslin Diabetes Center

Waleed Aldhahi · Joslin Diabetes Center

Dongsheng Cai · Joslin Diabetes Center

Elizabeth Tatro · Joslin Diabetes Center

Jongsoon Lee · Joslin Diabetes Center

Steven E. Shoelson ·

Abstract

These data demonstrate that salsalate improves in vivo glucose and lipid homeostasis, and support targeting of inflammation and NF-kappaB as a therapeutic approach in type 2 diabetes.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Atherosclerosis and Cardiovascular Diseases Microbial Metabolism and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical and Translational Science

Volume 1, Issue 1, pp. 36-43

DOI: 10.1111/j.1752-8062.2008.00026.x

Field-Weighted Citation Impact: 10.83