Effects of bone morphogenic protein 4 (BMP4) and its inhibitor, Noggin, on in vitromaturation and culture of bovine preimplantation embryos

Our results show that BMP4 is implicated in bovine oocytes maturation and embryo development. Moreover, our findings demonstrate, for the first time, that a correct balance of BMP signaling is needed for proper pre-implantation development of bovine embryos.