Human Endothelial Nitric Oxide Synthase Gene Delivery Promotes Angiogenesis in a Rat Model of Hindlimb Ischemia

200291 citationsJournal Articlebronze Open Access

Authors

Robert S. Smith · Medical University of South Carolina

Kuei-Fu Lin · Medical University of South Carolina

Jun Agata · Medical University of South Carolina

Lee Chao · Medical University of South Carolina

Julie Chao · Medical University of South Carolina

Abstract

Taken together, these results indicate that eNOS enhances angiogenesis and raises the potential of eNOS gene transfer for modulation of vascular insufficiency.

Topics & Keywords

Nitric Oxide and Endothelin Effects Angiogenesis and VEGF in Cancer Renin-Angiotensin System Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 22, Issue 8, pp. 1279-1285

DOI: 10.1161/01.atv.0000026613.18742.67

Field-Weighted Citation Impact: 4.70