Rhabdomyolysis and Acute Kidney Injury

20091,445 citationsReview

Authors

Xavier Bosch · Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Esteban Poch · Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Abstract

The causes of acute rhabdomyolysis include trauma, drugs, toxins, and certain infections. Acute kidney injury is a dangerous complication of severe rhabdomyolysis. This review summarizes current views on the pathogenesis of myoglobin-induced kidney injury as well as on its prevention and treatment.

Topics & Keywords

Muscle and Compartmental Disorders Poisoning and overdose treatments Neurological and metabolic disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 361, Issue 1, pp. 62-72

DOI: 10.1056/nejmra0801327

Field-Weighted Citation Impact: 55.19