Sinonasal mucosal melanoma: Molecular profile and therapeutic implications from a series of 32 cases

2012150 citationsJournal Articlegreen Open Access

Authors

Mario Turri–Zanoni · University of Brescia

Daniela Medicina · University of Brescia

Davide Lombardi · University of Brescia

Marco Ungari · University of Brescia

Piera Balzarini · University of Brescia

Cristina Rossini · University of Brescia

Wilma Pellegrini ·

Abstract

This molecular fingerprint strongly argues against the clinical efficacy of BRAF-inhibitors, but could candidate primary sinonasal mucosal melanomas to therapeutic strategies targeting RAS and KIT mutations or inhibiting PI3K-Akt-mTOR pathway.

Topics & Keywords

Infectious Diseases and Mycology Cutaneous Melanoma Detection and Management Cell Adhesion Molecules Research

Publication Details

Published in: Head & Neck

Volume 35, Issue 8, pp. 1066-1077

DOI: 10.1002/hed.23079

Field-Weighted Citation Impact: 12.83

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Sinonasal mucosal melanoma: Molecular profile and therapeutic implications from a series of 32 cases

Authors

Abstract

Topics & Keywords

Publication Details