The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis

2014548 citationsJournal Article

Authors

Philip L. Molyneaux · National Institute for Health Research

Michael J. Cox · Imperial College London

Saffron A.G. Willis‐Owen · Imperial College London

Patrick Mallia · National Health Service

Kirsty Russell · Imperial College London

Anne‐Marie Russell · National Institute for Health Research

Elissa Murphy

Abstract

IPF is characterized by an increased bacterial burden in BAL that predicts decline in lung function and death. Trials of antimicrobial therapy are needed to determine if microbial burden is pathogenic in the disease.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Pneumonia and Respiratory Infections Cystic Fibrosis Research Advances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 190, Issue 8, pp. 906-913

DOI: 10.1164/rccm.201403-0541oc

Field-Weighted Citation Impact: 35.56