Global N-Acetylaspartate in Normal Subjects, Mild Cognitive Impairment and Alzheimer's Disease Patients

201432 citationsJournal Article

Authors

Lidia Glodzik · New York University

Marc Sollberger · University Hospital of Basel

Achim Gass · University Hospital of Basel

Amit Gokhale · New York University

Henry Rusinek · New York University

James S. Babb · New York University

Jochen G. Hirsch ·

Abstract

Low WBNAA in MCI patients compared with cognitively normal contemporaries may indicate early neuronal damage accumulation and supports the notion of MCI as an early stage of AD. It also suggests WBNAA as a potential marker of early AD pathology.

Topics & Keywords

Alzheimer's disease research and treatments Dementia and Cognitive Impairment Research Folate and B Vitamins Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Alzheimer s Disease

Volume 43, Issue 3, pp. 939-947

DOI: 10.3233/jad-140609

Field-Weighted Citation Impact: 1.73