Evaluation of Subconjunctival Oculusgen Implantation as an Adjunct to Trabeculectomy

Purpose: To evaluate the efficacy and safety of subconjunctival oculusgen implantation when used during trabeculectomy Methods: In this prospective, nonrandomized, interventional case series, 10 eyes of 10 patients with medically uncontrolled open angle glaucoma were enrolled. Conventional fornix based trabeculectomy with implantation of subconjunctival biodegradable collagen implant (oculusgen) was performed in all patients. The preoperative best corrected visual acuity (BCVA), intraocular pressure (IOP) measurement and numbers of antiglaucoma medication were recorded. There were 7 postoperative follow-up visits within 6 months after surgery. After 6 months, follow-up visits were continued every 2-3 months. At each visit, the examination included measurements of BCVA and IOP, slit-lamp biomicroscopy, assessment of cell and flare, bleb evaluation and funduscopy. Any complications were recorded at the end of each examination. Data analysis was performed using SPSS software version 15. Results: Mean duration of follow-up was 11.9 months (range 6-26 months). Mean preoperative IOP was 19.3 mmHg (range 12-25 mmHg) with 2.9 number of IOP lowering medications (range 2-4)