Albumin Replacement in Patients with Severe Sepsis or Septic Shock

20141,302 citationsJournal Articlebronze Open Access

Authors

Pietro Caironi · Ospedale Maggiore

Gianni Tognoni · Mario Negri Sud Foundation

Serge Masson · Istituti di Ricovero e Cura a Carattere Scientifico

Roberto Fumagalli · University of Milano-Bicocca

Antonio Pesenti · University of Milano-Bicocca

Marilena Romero · Mario Negri Sud Foundation

Caterina Fanizza

Abstract

In patients with severe sepsis, albumin replacement in addition to crystalloids, as compared with crystalloids alone, did not improve the rate of survival at 28 and 90 days. (Funded by the Italian Medicines Agency; ALBIOS ClinicalTrials.gov number, NCT00707122.).

Topics & Keywords

Trauma, Hemostasis, Coagulopathy, Resuscitation Sepsis Diagnosis and Treatment Renal function and acid-base balance

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 370, Issue 15, pp. 1412-1421

DOI: 10.1056/nejmoa1305727

Field-Weighted Citation Impact: 78.74