cytoHubba: identifying hub objects and sub-networks from complex interactome

20146,605 citationsJournal Articlediamond Open Access

Authors

Chia-Hao Chin · Nanhua University

Shu-Hwa Chen · Institute of Information Science, Academia Sinica

Hsin-Hung Wu · Research Center for Information Technology Innovation, Academia Sinica

Chin-Wen Ho · National Central University

Ming‐Tat Ko · Institute of Information Science, Academia Sinica

Chung‐Yen Lin · Institute of Information Science, Academia Sinica

Abstract

CytoHubba provide a user-friendly interface to explore important nodes in biological networks. It computes all eleven methods in one stop shopping way. Besides, researchers are able to combine cytoHubba with and other plugins into a novel analysis scheme. The network and sub-networks caught by this topological analysis strategy will lead to new insights on essential regulatory networks and protein drug targets for experimental biologists. According to cytoscape plugin download statistics, the accumulated number of cytoHubba is around 6,700 times since 2010.

Topics & Keywords

Bioinformatics and Genomic Networks Computational Drug Discovery Methods Protein Structure and Dynamics

Publication Details

Published in: BMC Systems Biology

Volume 8, Issue S4, pp. S11-S11

DOI: 10.1186/1752-0509-8-s4-s11

Field-Weighted Citation Impact: 4.56

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cytoHubba: identifying hub objects and sub-networks from complex interactome

Authors

Abstract

Topics & Keywords

Publication Details