Pulmonary Microvascular Blood Flow in Mild Chronic Obstructive Pulmonary Disease and Emphysema. The MESA COPD Study

2015174 citationsJournal Articlegreen Open Access

Authors

Katja Hueper · Johns Hopkins University

Jens Vogel‐Claussen · Medizinische Hochschule Hannover

Megha A. Parikh

John H. M. Austin · Pediatrics and Genetics

David A. Bluemke · National Institutes of Health Clinical Center

James Carr · Pediatrics and Genetics

Jiwoong Choi · University of Iowa

Abstract

PMBF was reduced in mild COPD, including in regions of lung without frank emphysema, and may represent a distinct pathological process from small airways disease. PMBF may provide an imaging biomarker for therapeutic strategies targeting the pulmonary microvasculature.

Topics & Keywords

Chronic Obstructive Pulmonary Disease (COPD) Research Atomic and Subatomic Physics Research Heart Rate Variability and Autonomic Control

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 192, Issue 5, pp. 570-580

DOI: 10.1164/rccm.201411-2120oc

Field-Weighted Citation Impact: 12.68