Probiotic Prophylaxis in Predicted Severe Acute Pancreatitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial

In patients with predicted severe acute pancreatitis, probiotic prophylaxis with this combination of probiotic strains did not reduce the risk of infectious complications and was associated with an increased risk of mortality. Probiotic prophylaxis should therefore not be administered in this category of patients. ( Lancet. 2008;371(9613):651-659) MGH Besselink, HC van Santvoort, E Buskens, et al, for the Dutch Acute Pancreatitis Study Group.