Coexpression of gastrin and gastrin receptors (CCK-B and ΔCCK-B) in gastrointestinal tumour cell lines

199888 citationsJournal Articlebronze Open Access

Authors

Daniel F. McWilliams · Cancer Research UK

Abstract

The truncated gastrin receptor, delta CCK-B, is coexpressed with gastrin in 8/13 GI tumour cell lines. Gastrin and CCK-B receptor isoforms may be involved in maintaining autocrine/paracrine growth pathways in GI cancer cells.

Topics & Keywords

Neuroendocrine Tumor Research Advances Helicobacter pylori-related gastroenterology studies Neuropeptides and Animal Physiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 42, Issue 6, pp. 795-798

DOI: 10.1136/gut.42.6.795

Field-Weighted Citation Impact: 5.40