Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

2005140 citationsJournal Article

Authors

Albrecht Berkessel · University of Cologne

Santanu Mukherjee · University of Cologne

Thomas N. Müller · University of Cologne

Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two “matched” elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

Topics & Keywords

Synthesis and Reactions of Organic Compounds Analytical Chemistry and Chromatography Chemical Reaction Mechanisms

Publication Details

Published in: Chemical Communications

DOI: 10.1039/b418666d

Field-Weighted Citation Impact: 11.38

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Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Authors

Abstract

Topics & Keywords

Publication Details