Complement C3 Variant and the Risk of Age-Related Macular Degeneration

2007825 citationsJournal Articlebronze Open Access

Authors

John R.W. Yates · Addenbrooke's Hospital

Tiina Sepp · University of Cambridge

Baljinder K. Matharu · University of Cambridge

Jane C. Khan · University of Cambridge

Deborah A. Thurlby · University of Cambridge

Humma Shahid · University of Cambridge

David Clayton ·

Abstract

Complement C3 is important in the pathogenesis of age-related macular degeneration. This finding further underscores the influence of the complement pathway in the pathogenesis of this disease.

Topics & Keywords

Retinal Diseases and Treatments Complement system in diseases Ocular Diseases and Behçet’s Syndrome

Publication Details

Published in: New England Journal of Medicine

Volume 357, Issue 6, pp. 553-561

DOI: 10.1056/nejmoa072618

Field-Weighted Citation Impact: 58.90

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Complement C3 Variant and the Risk of Age-Related Macular Degeneration

Authors

Abstract

Topics & Keywords

Publication Details