Immunologic Aspects of Chronic Obstructive Pulmonary Disease

2009803 citationsReviewgreen Open Access

Authors

Manuel G. Cosío · Hospital Universitario Son Dureta

Àlvar Agustí · Centro de Investigación Biomédica en Red de Enfermedades Respiratorias

Abstract

This review is an account of how pulmonary damage caused by cigarette smoke and other environmental toxins can incite inflammatory and immunologic reactions that culminate in chronic obstructive pulmonary disease (COPD). The authors present evidence that autoimmunity has a role in the development of COPD.

Topics & Keywords

Chronic Obstructive Pulmonary Disease (COPD) Research Pediatric health and respiratory diseases Asthma and respiratory diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 23, pp. 2445-2454

DOI: 10.1056/nejmra0804752

Field-Weighted Citation Impact: 52.57