Acute Human Lethal Toxicity of Agricultural Pesticides: A Prospective Cohort Study

2010330 citationsJournal Articlegold Open Access

Authors

Andrew Dawson · University of Peradeniya

Michael Eddleston · University of Edinburgh

Lalith Senarathna · South Asian Clinical Toxicology Research Collaboration

Fahim Mohamed · South Asian Clinical Toxicology Research Collaboration

Indika Gawarammana · South Asian Clinical Toxicology Research Collaboration

Steven J. Bowe · University of Newcastle Australia

Gamini Manuweera

Abstract

the human data provided toxicity rankings for some pesticides that contrasted strongly with the WHO toxicity classification based on rat toxicity. Basing regulation on human toxicity will make pesticide poisoning less hazardous, preventing hundreds of thousands of deaths globally without compromising agricultural needs. Ongoing monitoring of patterns of use and clinical toxicity for new pesticides is needed to identify highly toxic pesticides in a timely manner.

Topics & Keywords

Pesticide Exposure and Toxicity Poisoning and overdose treatments Insect and Pesticide Research

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: PLoS Medicine

Volume 7, Issue 10, pp. e1000357-e1000357

DOI: 10.1371/journal.pmed.1000357

Field-Weighted Citation Impact: 22.75