Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

2011322 citationsJournal Articlegold Open Access

Authors

Hiromi Nabeshi · Osaka University

Tomoaki Yoshikawa · Osaka University

Keigo Matsuyama · National Institute of Biomedical Innovation, Health and Nutrition

Yasutaro Nakazato · National Institute of Biomedical Innovation, Health and Nutrition

Saeko Tochigi · National Institute of Biomedical Innovation, Health and Nutrition

Sayuri Kondoh · National Institute of Biomedical Innovation, Health and Nutrition

Abstract

Thus, particle size affects amorphous silica-induced ROS generation and DNA damage of HaCaT cells. We believe clarification of the endocytosis pathway of nSP will provide useful information for hazard assessment as well as the design of safer forms of nSPs.

Topics & Keywords

Nanoparticles: synthesis and applications Medical and Biological Ozone Research Selenium in Biological Systems

Publication Details

Published in: Particle and Fibre Toxicology

Volume 8, Issue 1, pp. 1-1

DOI: 10.1186/1743-8977-8-1

Field-Weighted Citation Impact: 18.07

Command Palette

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

Authors

Abstract

Topics & Keywords

Publication Details