<i>Pseudomonas aeruginosa</i> in Chronic Obstructive Pulmonary Disease

2008280 citationsJournal Article

Authors

Timothy F. Murphy · Buffalo VA Medical Center

Aimee L. Brauer

Karen Eschberger · VA Western New York Healthcare System

Phyllis Lobbins · VA Western New York Healthcare System

Lori Grove

Xueya Cai · University at Buffalo, State University of New York

Sanjay Sethi · VA Western New York Healthcare System

Abstract

Two distinct patterns of carriage by P. aeruginosa were observed: (1) short-term colonization followed by clearance and (2) long-term persistence. Mucoid strains showed persistence. Acquisition of P. aeruginosa is associated with the occurrence of an exacerbation. Serum antibody responses do not mediate clearance of P. aeruginosa.

Topics & Keywords

Cystic Fibrosis Research Advances Inhalation and Respiratory Drug Delivery Nosocomial Infections in ICU

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 177, Issue 8, pp. 853-860

DOI: 10.1164/rccm.200709-1413oc

Field-Weighted Citation Impact: 15.93