Persistent Organochlorine Pesticides and Risk of Testicular Germ Cell Tumors

2008207 citationsJournal Article

Authors

Katherine A. McGlynn · Department of Health and Human Services

Sabah M. Quraishi · Walter Reed Army Institute of Research

Barry I. Graubard · Walter Reed Army Institute of Research

Jean‐Philippe Weber · Institut National de Santé Publique du Québec

Mark V. Rubertone · U.S. Army Center for Health Promotion and Preventive Medicine

Ralph L. Erickson · Walter Reed Army Institute of Research

Abstract

Increased exposure to p,p'-DDE may be associated with the risk of both seminomatous and nonseminomatous TGCTs, whereas exposure to chlordane compounds and metabolites may be associated with the risk of seminoma. Because evidence suggests that TGCT is initiated in very early life, it is possible that exposure to these persistent organic pesticides during fetal life or via breast feeding may increase the risk of TGCT in young men.

Topics & Keywords

Pesticide Exposure and Toxicity Sperm and Testicular Function Carcinogens and Genotoxicity Assessment

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 100, Issue 9, pp. 663-671

DOI: 10.1093/jnci/djn101

Field-Weighted Citation Impact: 17.87

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Persistent Organochlorine Pesticides and Risk of Testicular Germ Cell Tumors

Authors

Abstract

Topics & Keywords

Publication Details