Novel Immunoassay for Quantification of Brain Natriuretic Peptide and Its Precursor in Human Blood

200839 citationsJournal Article

Authors

Natalia N Tamm · HyTest (Finland)

Karina R Seferian · HyTest (Finland)

Alexander G Semenov · Lomonosov Moscow State University

Kadriya S Mukharyamova

Ekaterina V Koshkina · Moscow City Hospital No 29

Mihail I Krasnoselsky

Alexander B. Postnikov · HyTest (Finland)

Daria V. Serebryanaya

Abstract

We have developed this sensitive single-epitope sandwich assay for detecting BNP, proBNP, and their fragments in human blood. This assay appears promising for use in clinical studies to assist in triage, management, and outcomes assessment in heart failure patients.

Topics & Keywords

Viral Infections and Immunology Research Peptidase Inhibition and Analysis Monoclonal and Polyclonal Antibodies Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 54, Issue 9, pp. 1511-1518

DOI: 10.1373/clinchem.2007.100545

Field-Weighted Citation Impact: 1.56