Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study

2014179 citationsJournal Articlebronze Open Access

Authors

Cecilie Jacobsen · Stavanger University Hospital

Jesper Hagemeier · University at Buffalo, State University of New York

Kjell-Morten Myhr · University of Bergen

Harald Nyland · University of Bergen

Kirsten Lode · Stavanger University Hospital

Niels Bergsland · University at Buffalo, State University of New York

Deepa P. Ramasamy

Abstract

This long-term study shows that whole brain, cortical and putamen atrophy occurs throughout the 10-year follow-up of this MS cohort and is more pronounced in the group that showed disability progression at 5, but not at 10 years of follow-up. Overall, GM atrophy showed better association with disease progression than WM atrophy over 5-year and 10-year follow-up.

Topics & Keywords

Multiple Sclerosis Research Studies Ultrasound Imaging and Elastography Rheumatoid Arthritis Research and Therapies

Publication Details

Published in: Journal of Neurology Neurosurgery & Psychiatry

Volume 85, Issue 10, pp. 1109-1115

DOI: 10.1136/jnnp-2013-306906

Field-Weighted Citation Impact: 12.90

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Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study

Authors

Abstract

Topics & Keywords

Publication Details