Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4

2006832 citationsJournal Articlebronze Open Access

Authors

Kimberly E Beck · National Cancer Institute

Joseph Blansfield · National Institutes of Health

Khoi Q. Tran · National Institutes of Health

Andrew L. Feldman · National Cancer Institute

Marybeth S. Hughes · National Institutes of Health

Richard E. Royal · National Cancer Institute

Udai S. Kammula

Abstract

CTLA4 seems to be a significant component of tolerance to tumor and in protection against immune mediated enterocolitis and these phenomena are significantly associated in cancer patients.

Topics & Keywords

Cancer Immunotherapy and Biomarkers T-cell and B-cell Immunology Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 24, Issue 15, pp. 2283-2289

DOI: 10.1200/jco.2005.04.5716

Field-Weighted Citation Impact: 19.01