Feasibility and Efficacy of Molecular Analysis-Directed Individualized Therapy in Advanced Non–Small-Cell Lung Cancer

2007181 citationsJournal Article

Authors

George R. Simon · Moffitt Cancer Center

Anupama Sharma · University of South Florida

Xueli Li · University of South Florida

Todd R. Hazelton · Moffitt Cancer Center

Frank Walsh · Moffitt Cancer Center

Charles C. Williams · University of South Florida

Alberto Chiappori ·

Abstract

Therapeutic decision making based on RRM1 and ERCC1 gene expression for patients with advanced NSCLC is feasible and promising for improvement in patient outcome

Topics & Keywords

RNA modifications and cancer Lung Cancer Treatments and Mutations Metal-Catalyzed Oxygenation Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 25, Issue 19, pp. 2741-2746

DOI: 10.1200/jco.2006.08.2099

Field-Weighted Citation Impact: 12.04