Costimulation Blockade with Belatacept in Renal Transplantation

2005852 citationsJournal Articlebronze Open Access

Authors

Flavio Vincenti · University of San Francisco

Christian P. Larsen · University of Alberta

Antoine Dürrbach · Inserm

Thomas Wekerle · University of Alberta

Björn Nashan · University of Alberta

Gilles Blancho · University of Alberta

Philippe Lang ·

Abstract

Belatacept, an investigational selective costimulation blocker, did not appear to be inferior to cyclosporine as a means of preventing acute rejection after renal transplantation. Belatacept may preserve the glomerular filtration rate and reduce the rate of chronic allograft nephropathy.

Topics & Keywords

Renal Transplantation Outcomes and Treatments HIV/AIDS drug development and treatment Pneumocystis jirovecii pneumonia detection and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 353, Issue 8, pp. 770-781

DOI: 10.1056/nejmoa050085

Field-Weighted Citation Impact: 28.23