Growth control of the eukaryote cell: a systems biology study in yeast

2007280 citationsJournal Articlegold Open Access

Authors

Juan I. Castrillo · University of Manchester

Leo Zeef · University of Manchester

David C. Hoyle · University of Manchester

Nianshu Zhang · University of Manchester

Andrew Hayes · University of Manchester

David C. Gardner · University of Manchester

Michael Cornell ·

Abstract

This work constitutes a first comprehensive systems biology study on growth-rate control in the eukaryotic cell. The results have direct implications for advanced studies on cell growth, in vivo regulation of metabolic fluxes for comprehensive metabolic engineering, and for the design of genome-scale systems biology models of the eukaryotic cell.

Topics & Keywords

Fungal and yeast genetics research RNA and protein synthesis mechanisms Genomics and Chromatin Dynamics

UN Sustainable Development Goals

Reduced inequalitiesPeace, Justice and strong institutions

Publication Details

Published in: Journal of Biology

Volume 6, Issue 2, pp. 4-4

DOI: 10.1186/jbiol54

Field-Weighted Citation Impact: 11.52