Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism

2011132 citationsJournal Articlebronze Open Access

Authors

Masahiro Koizumi · Tokai University

Hirotaka Komaba · Tokai University

Shigeo Nakanishi · Kobe University

A. Fujimori · Chibune General Hospital

Masafumi Fukagawa · Tokai University

Abstract

Cinacalcet lowers serum FGF23 in haemodialysis patients with SHPT independently of the effects of active vitamin D. Pretreatment FGF23 cannot predict treatment response to cinacalcet in this setting. The precise mechanism of FGF23 reduction by cinacalcet and its clinical impact on outcomes in patients remain to be investigated.

Topics & Keywords

Parathyroid Disorders and Treatments Pancreatitis Pathology and Treatment Magnesium in Health and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nephrology Dialysis Transplantation

Volume 27, Issue 2, pp. 784-790

DOI: 10.1093/ndt/gfr384

Field-Weighted Citation Impact: 8.62