Adjusting Mortality for Loss to Follow-Up: Analysis of Five ART Programmes in Sub-Saharan Africa

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Authors

Martin W. G. Brinkhof · Institute of Social and Preventive Medicine

Ben D. Spycher · Institute of Social and Preventive Medicine

Constantin T. Yiannoutsos · Indiana University

Ralf Weigel · Kamuzu Central Hospital

Robin Wood · Desmond Tutu HIV Foundation

Eugène Messou · Programme PAC-CI

Andrew Boulle

Abstract

Naïve survival analysis ignoring excess mortality in patients lost to follow-up may greatly underestimate overall mortality, and bias ART programme evaluations. Adjusted mortality estimates can be obtained based on excess mortality rates in patients lost to follow-up.

Topics & Keywords

HIV/AIDS Research and Interventions HIV Research and Treatment HIV-related health complications and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 5, Issue 11, pp. e14149-e14149

DOI: 10.1371/journal.pone.0014149

Field-Weighted Citation Impact: 3.51