Prospective Study of Cyclin D1 Overexpression in Barrett's Esophagus: Association With Increased Risk of Adenocarcinoma

2000248 citationsJournal Articlebronze Open Access

Authors

K Bani-Hani · Leeds General Infirmary

I. G. Martin · Leeds General Infirmary

Laura J. Hardie · Leeds General Infirmary

N Mapstone · Leeds General Infirmary

John A. G. Briggs · Leeds General Infirmary

D Forman · Leeds General Infirmary

C. P. Wild ·

Abstract

Cyclin D1-positive staining could be a useful biomarker in identifying Barrett's esophagus patients at high risk of esophageal adenocarcinoma. Given the complexity of genetic alterations in the natural history of this cancer, additional biomarkers will be required to increase the sensitivity and specificity of molecular diagnosis.

Topics & Keywords

Esophageal Cancer Research and Treatment Esophageal and GI Pathology Gastric Cancer Management and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 92, Issue 16, pp. 1316-1321

DOI: 10.1093/jnci/92.16.1316

Field-Weighted Citation Impact: 14.54