Evolutionary conservation of sequence and secondary structures in CRISPR repeats

2007451 citationsJournal Articlegold Open Access

Authors

Philip Hugenholtz · Joint Genome Institute

Abstract

We show that the repeat-based classification corresponds to, and expands upon, a previously reported CAS gene-based classification, including specific relationships between CRISPR and CAS subtypes.

Topics & Keywords

CRISPR and Genetic Engineering RNA and protein synthesis mechanisms Evolution and Genetic Dynamics

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Genome biology

Volume 8, Issue 4, pp. R61-R61

DOI: 10.1186/gb-2007-8-4-r61

Field-Weighted Citation Impact: 6.83