Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

2014105 citationsJournal Articlebronze Open Access

Authors

Xiang Xiao · Zhejiang Academy of Medical Sciences

D Mruk · Population Council

Elizabeth I. Tang · Population Council

Chris K.C. Wong · Hong Kong Baptist University

Wei‐Ming Lee · MandalMed (United States)

Constance M. John · MandalMed (United States)

P. J. Turek ·

Abstract

Human Sertoli cells cultured in vitro provide a robust model to monitor environmental toxicant-mediated disruption of Sertoli cell BTB function and to study the mechanism(s) of toxicant-induced testicular dysfunction.

Topics & Keywords

Sperm and Testicular Function Renal and related cancers Reproductive Biology and Fertility

Publication Details

Published in: Human Reproduction

Volume 29, Issue 6, pp. 1279-1291

DOI: 10.1093/humrep/deu011

Field-Weighted Citation Impact: 12.35

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Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

Authors

Abstract

Topics & Keywords

Publication Details