<i>In Vivo</i> Osseointegration of Nano-Designed Composite Coatings on Titanium Implants

201193 citationsJournal Article

Authors

Sybille Facca · Florida International University

Debrupa Lahiri · Florida International University

Florence Fioretti · Biomatériaux et Bioingénierie

Nadia Messadeq · Institut de génétique et de biologie moléculaire et cellulaire

Didier Mainard · Université de Lorraine

Nadia Benkirane-Jessel · Centre National de la Recherche Scientifique

Arvind Agarwal

Abstract

This is the first in vivo study of plasma-sprayed carbon nanotube (CNT)-reinforced hydroxyapatite (HA) coating on titanium implants embedded in rodents' bone. No adverse effect or cytotoxicity of CNT addition on bone tissues and cells was observed. Normal bone growth was observed around HA-CNT-coated implants. CNT addition induces higher osseointegration as compared to HA. Elastic modulus of new bone was compared with the modulus of HA-CNT/bone interface to understand the mechanical integrity of the implant.

Topics & Keywords

Bone Tissue Engineering Materials Graphene and Nanomaterials Applications Laser-Ablation Synthesis of Nanoparticles

Publication Details

Published in: ACS Nano

Volume 5, Issue 6, pp. 4790-4799

DOI: 10.1021/nn200768c

Field-Weighted Citation Impact: 3.65

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<i>In Vivo</i> Osseointegration of Nano-Designed Composite Coatings on Titanium Implants

Authors

Abstract

Topics & Keywords

Publication Details