Decreased levels of genuine large free hCG alpha in men presenting with abnormal semen analysis

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Authors

Christoph Zenzmaier · Austrian Academy of Sciences

R. Gerth · Austrian Academy of Sciences

Matthias S. Gruschwitz · Friedrich-Alexander-Universität Erlangen-Nürnberg

Herbert Lindner · Innsbruck Medical University

Eugen Plas · Ludwig Boltzmann Institute for Digital Health and Prevention

Peter Berger · Austrian Academy of Sciences

Abstract

The findings indicate a pathophysiological relevance of hCG, particularly its free alpha subunit, in spermatogenesis. The alternative glycosylation pattern on the free large hCG alpha in seminal plasma might reflect a modified function of this subunit in the male reproductive tract.

Topics & Keywords

Hypothalamic control of reproductive hormones Sexual Differentiation and Disorders Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Reproductive Biology and Endocrinology

Volume 9, Issue 1, pp. 114-114

DOI: 10.1186/1477-7827-9-114

Field-Weighted Citation Impact: 2.31