Norbornenes in Inverse Electron‐Demand Diels–Alder Reactions

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Authors

Milan Vrábel

Patrick Kölle

Korbinian Brunner

Michael J. Gattner

Verónica López‐Carrillo · Ludwig-Maximilians-Universität München

Regina de Vivie‐Riedle · Ludwig-Maximilians-Universität München

Thomas Carell · Ludwig-Maximilians-Universität München

Abstract

Significant differences in the reactivity of norbornene derivatives in the inverse electron-demand Diels-Alder reaction with tetrazines were revealed by kinetic studies. Substantial rate enhancement for the exo norbornene isomers was observed. Quantum-chemical calculations were used to rationalize and support the observed experimental data.

Topics & Keywords

Click Chemistry and Applications Chemical Synthesis and Analysis Fluorine in Organic Chemistry

Publication Details

Published in: Chemistry - A European Journal

Volume 19, Issue 40, pp. 13309-13312

DOI: 10.1002/chem.201301838

Field-Weighted Citation Impact: 3.84

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Norbornenes in Inverse Electron‐Demand Diels–Alder Reactions

Authors

Abstract

Topics & Keywords

Publication Details