Neutral Desorption Sampling of Living Objects for Rapid Analysis by Extractive Electrospray Ionization Mass Spectrometry

MS comes to life: A novel method to sample surfaces of biological objects uses a neutral gas beam for in vivo EESI mass spectrometric analysis without sample pretreatment (see picture; QTOF=quadropole time-of-flight). The sampling process results in rapid in vivo analyses with reduced ion suppression and without chemical contamination. This strategy can be used in food quality monitoring, homeland security, metabolomics, and clinical diagnosis. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z702200_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.