Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

201396 citationsJournal Articlegold Open Access

Authors

Sylene Coutinho Rampche de Carvalho · Universidade de Pernambuco

Maria Tereza Cartaxo Muniz · Universidade de Pernambuco

Maria Deozete Vieira Siqueira · Universidade de Pernambuco

Érika Rabelo Forte de Siqueira · Universidade de São Paulo

Adriana Vieira Gomes · Universidade de Pernambuco

Karina Alves da Silva · Universidade de Pernambuco

Laís Carvalho Luma Bezerra

Abstract

Our results indicate that plasma Hcy was higher in NAFLD than controls. The MTHFR C677T and A1298C polymorphisms did not differ significantly between groups, despite the 677TT homozygous frequency was higher in patients (17.14%) than in controls (677TT = 4.44%) (p > 0.05). The suggested genetic susceptibility to the MTHFR C677T and A1298C should be confirmed in large population based studies.

Topics & Keywords

Liver Disease Diagnosis and Treatment Folate and B Vitamins Research Liver Disease and Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nutrition Journal

Volume 12, Issue 1, pp. 37-37

DOI: 10.1186/1475-2891-12-37

Field-Weighted Citation Impact: 5.29