Stoichiometry of Gata4, Mef2c, and Tbx5 Influences the Efficiency and Quality of Induced Cardiac Myocyte Reprogramming

2014231 citationsJournal Articlebronze Open Access

Authors

Li Wang · Council of Independent Colleges

Ziqing Liu · Council of Independent Colleges

Chaoying Yin · Council of Independent Colleges

Huda Asfour · Council of Independent Colleges

Olivia Chen · Council of Independent Colleges

Yanzhen Li · Council of Independent Colleges

Nenad Bursac

Abstract

Our results demonstrate that stoichiometry of G, M, T protein expression influences the efficiency and quality of iCM reprogramming. The established optimal G, M, T expression condition will provide a valuable platform for future iCM studies.

Topics & Keywords

Congenital heart defects research Pluripotent Stem Cells Research Neuroscience and Neural Engineering

Publication Details

Published in: Circulation Research

Volume 116, Issue 2, pp. 237-244

DOI: 10.1161/circresaha.116.305547

Field-Weighted Citation Impact: 9.38

Command Palette

Stoichiometry of Gata4, Mef2c, and Tbx5 Influences the Efficiency and Quality of Induced Cardiac Myocyte Reprogramming

Authors

Abstract

Topics & Keywords

Publication Details