A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis

20101,664 citationsJournal Articlebronze Open Access

Authors

Hjalmar C. van Santvoort · University Medical Center Utrecht

Marc G. Besselink · University Medical Center Utrecht

Olaf J. Bakker · University Medical Center Utrecht

H. Sijbrand Hofker · University Medical Center Groningen

Marja A. Boermeester · Academic Medical Center

Cornelis H.C. Dejong · Maastricht University

Harry van Goor

Abstract

A minimally invasive step-up approach, as compared with open necrosectomy, reduced the rate of the composite end point of major complications or death among patients with necrotizing pancreatitis and infected necrotic tissue. (Current Controlled Trials number, ISRCTN13975868.)

Topics & Keywords

Pancreatitis Pathology and Treatment Gastrointestinal disorders and treatments Pancreatic and Hepatic Oncology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 362, Issue 16, pp. 1491-1502

DOI: 10.1056/nejmoa0908821

Field-Weighted Citation Impact: 80.21