Errors and Reproducibility of DNA Array-Based Detection of Allelic Variants in ADME Genes: PHARMAchip™

201017 citationsJournal Article

Authors

Elisabet Cuyàs · Universitat Autònoma de Barcelona

Estíbaliz Olano-Martin

Olha Khymenets · Pompeu Fabra University

Magı́ Farré · Universitat Autònoma de Barcelona

Rafael de la Torre

Abstract

Although these tests are based on different methodological approaches, we have found a high concordance of results between both methods. Some of the discrepancies between tests were related to allelic variants not monitored in a particular microarray and the quality of the genomic DNA used.

Topics & Keywords

Pharmacogenetics and Drug Metabolism Biochemical and Molecular Research Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacogenomics

Volume 11, Issue 2, pp. 257-266

DOI: 10.2217/pgs.09.165

Field-Weighted Citation Impact: 4.23