Epstein-Barr virus replication within pulmonary epithelial cells in cryptogenic fibrosing alveolitis.

1995164 citationsJournal Articlebronze Open Access

Authors

J. Egan · Wythenshawe Hospital

James P. Stewart · Wythenshawe Hospital

P S Hasleton · Wythenshawe Hospital

J. R. Arrand · Wythenshawe Hospital

K B Carroll · Wythenshawe Hospital

Ashley Woodcock · Wythenshawe Hospital

Abstract

This is the first report of in vivo EBV replication within epithelial cells of the lower respiratory tract in an immunocompetent human host. Furthermore, this suggests that EBV may be an immune trigger or contribute to lung injury in cryptogenic fibrosing alveolitis, thus offering a potential new avenue of treatment.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Parvovirus B19 Infection Studies Medical Imaging and Pathology Studies

UN Sustainable Development Goals

Responsible consumption and production

Publication Details

Published in: Thorax

Volume 50, Issue 12, pp. 1234-1239

DOI: 10.1136/thx.50.12.1234

Field-Weighted Citation Impact: 5.91