Multiple Serotonergic Brainstem Abnormalities in Sudden Infant Death Syndrome

2006495 citationsJournal Article

Authors

David S. Paterson · Boston Children's Hospital

Felicia Trachtenberg

Abstract

Medullary 5-HT pathology in SIDS is more extensive than previously delineated, potentially including abnormal 5-HT neuron firing, synthesis, release, and clearance. This study also provides preliminary neurochemical evidence that may help explain the increased vulnerability of boys to SIDS.

Topics & Keywords

Neuroscience of respiration and sleep Neuroendocrine regulation and behavior Infant Health and Development

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 296, Issue 17, pp. 2124-2124

DOI: 10.1001/jama.296.17.2124

Field-Weighted Citation Impact: 18.23