Follow-up of 89 Asymptomatic Patients With Adrenoleukodystrophy Treated With Lorenzo’s Oil

2005242 citationsJournal Article

Authors

Hugo W. Moser · Johns Hopkins University

Gerald V. Raymond

Shou‐En Lu · Rutgers, The State University of New Jersey

Larry R. Muenz · Westat (United States)

Ann B. Moser · Kennedy Krieger Institute

Jiahong Xu · Westat (United States)

Richard O. Jones · Kennedy Krieger Institute

Abstract

In this single-arm study, hexacosanoic acid reduction by Lorenzo's oil was associated with reduced risk of developing MRI abnormalities. We recommend Lorenzo's oil therapy in asymptomatic boys with X-linked adrenoleukodystophy who have normal brain MRI results.

Topics & Keywords

Peroxisome Proliferator-Activated Receptors Eicosanoids and Hypertension Pharmacology Alcoholism and Thiamine Deficiency

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of Neurology

Volume 62, Issue 7, pp. 1073-1073

DOI: 10.1001/archneur.62.7.1073

Field-Weighted Citation Impact: 7.56