Metformin treatment before and during IVF or ICSI in women with polycystic ovary syndrome

2014228 citationsReviewgreen Open Access

Authors

L.O. Tso · Universidade Federal de São Paulo

Michael Costello · Royal Hospital for Women

L.E.T. Albuquerque · Centro de Reprodução Humana Prof. Franco Junior

Régis B Andriolo · Universidade do Estado do Pará

Abstract

This review found no conclusive evidence that metformin treatment before or during ART cycles improved live birth rates in women with PCOS. However, the use of this insulin-sensitising agent increased clinical pregnancy rates and decreased the risk of OHSS.

Topics & Keywords

Ovarian function and disorders Reproductive Biology and Fertility Assisted Reproductive Technology and Twin Pregnancy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cochrane Database of Systematic Reviews

Volume 12, Issue 11, pp. CD006105-CD006105

DOI: 10.1002/14651858.cd006105.pub3

Field-Weighted Citation Impact: 28.69