Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia

20041,376 citationsJournal Articlebronze Open Access

Authors

Peter J.M. Valk · Erasmus MC

Roel G.W. Verhaak · Erasmus MC

M. Antoinette Beijen · Erasmus MC

Claudia Erpelinck-Verschueren · Erasmus MC

Sahar Barjesteh van Waalwijk van Doorn-Khosrovani

Judith M. Boer · Leiden University Medical Center

H. Berna Beverloo · Erasmus MC

Abstract

Gene-expression profiling allows a comprehensive classification of AML that includes previously identified genetically defined subgroups and a novel cluster with an adverse prognosis.

Topics & Keywords

Acute Myeloid Leukemia Research Chronic Myeloid Leukemia Treatments Bone and Joint Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 350, Issue 16, pp. 1617-1628

DOI: 10.1056/nejmoa040465

Field-Weighted Citation Impact: 47.21